Welcome to our comprehensive NFL Week 1 predictions for the 2025 season. Our expert analysis provides detailed insights into every matchup, including predicted scores, key player matchups, and strategic considerations that could impact the outcome of each game.

Each prediction is based on advanced statistical models that analyze offensive and defensive rankings, player performance metrics, historical matchup data, and current team dynamics. Whether you're looking for betting insights, fantasy football guidance, or simply want to understand what to expect in Week 1, our predictions provide the analysis you need.

The games are organized by day and time slots to help you plan your viewing schedule. Each game card displays the predicted final score, venue information, and key matchup details.

Click on any game card below to view our detailed analysis, including offensive and defensive breakdowns, player matchups, and comprehensive game predictions. Our Week 1 predictions are updated regularly to reflect the latest team news, injury reports, and roster changes.